Radiology

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Summary of Activity

We study for developing novel diagnostic and therapeutic methods to solve clinical problems in our department. The main study themes are early diagnosis, differential diagnosis, and pathophysiological analysis by diagnostic imaging, developing novel methods in diagnostic imaging, interventional radiology (IVR), and radiation therapy. Every clinical study is conducted in cooperation with other clinical departments.

Research Subject

• ?Early and differential diagnosis, pathophysiological analysis by diagnostic imaging
• ?Development of novel methods in diagnostic imaging, IVR, and modality
• ?Development of novel curative radiation therapy preserving organ functions

Outlook for Research

Early recognition by less-invasive examination; then, expecting complete cure without functional loss by less-invasive therapy. Our studies in radiology department will promote bright future in patient-friendly medical care.

Major Publications

1. Tsukahara Y, Okajima Y, Ymada A, Momose M, Uehara T, Shimizu A, Soejima Y, Fujinaga Y: The peritumoral hypointense rim around hepatocellular carcinoma on T2*-weighted magnetic resonance imaging: radiologic-pathologic correlation. World J Surg Oncol: 19(1):41,2021

2. Ohya A, Kobara H, Miyamoto T, Komatsu M, Shiozawa T, Fujinaga Y: Usefulness of the ‘cosmos pattern’ for differentiating between cervical gastric-type mucin-positive lesions and other benign cervical cystic lesions in magnetic resonance images. J Obstet Gynaecol Res 47(2): 745-756, 2021

3. Yanagisawa S, Takahashi Y, Sasaki J, Takasone K, Yoshie K, Koyama J, Katoh N, Yazaki M, Kuwahara K, Fujinaga Y, Sekijima Y: Absolute quantitative analysis of cardiac amyloidosis using SPECT/CT with 99mTc-pyrophosphate. Amyloid 28(3): 213-214, 2021

4. Matushita H, Ozawa T, Sekiguchi N, Fukushima T, Kobayashi T, Kanda S, Koizumi T: A Case of Sinonasal Undifferentiated Carcinoma Successfully Responding to Chemoradiotherapy. The Shinshu Medical Journal 69(3):121-126. 2021

5. Ohya A, Matoba H, Fujinaga Y, Nakayama J: Decreased Gastric Gland Mucin-specific O-glycans Are Involved in the Progression of Ovarian Primary Mucinous Tumours. Acta Histochem Cytochem 54(4): 115-122, 2021

6. Tokoro H, Yamada A, Suzuki T, Kito Y, Adachi Y, Hayashihara H, Nickel MD, Maruyama K, Fujinaga Y: Usefulness of breath-hold compressed sensing accelerated three-dimensional magnetic resonance cholangio-pancreatography (MRCP) added to respiratory-gating conventional MRCP. Eur J Radiol 122: 108765, 2020

7. Koiwai K, Endo Y, Mizuhata K, Ina H, Fukazawa A, Ozawa T, Fujinaga Y: Ten-Year Experience of Stereotactic Body Radiotherapy at a Single Institution: Impact of Technological Development on the Outcome of Patients with Early Lung Cancer: Technol Cancer Res Treat: Vol 19: 1-7, 2020

8. Yamada A, Oyama K, Fujita S, Yoshizawa E, Ichinohe F, Komatsu D, Fujinaga Y: Dynamic contrast-enhanced computed tomography diagnosis of primary liver cancers using transfer learning of pretrained convolutional neural networks: Is registration of multiphasic images necessary? Int J Comput Assist Radiol Surg 14(8): 1295-1301, 2019

9. Suzuki T, Yamada A, Komatsu D, Kurozumi M, Fujinaga Y, Ueda K, Miyagawa S, Kadoya M: Evaluation of splenic perfusion and spleen size using dynamic computed tomography: Usefulness in assessing degree of liver fibrosis. Hepatol Res 48(1): 87-93, 2018

10. Kawakami S, Fujinaga Y, Yanagisawa S, Kadoya M, Kobayashi A, Oguchi K: A case of pancreatic carcinoma with bilateral hilar 18F-FDG and 67Ga hyper accumulation. The Shinshu Medical Journal 66(2): 151-155, 2018

11. Fukazawa A, Koiwai K, Ozawa T, Matsushita H, Kadoya M: Predictive factors for deterioration of lower urinary tract symptoms after Iodine-125 brachytherapy in prostate cancer patients. The Shinshu Medical Journal 66(2): 131-137, 2018

12. Kurozumi M, Fujinaga Y, Kitou Y, Yamada A, Ohya A, Adachi Y, Tsukahara Y, Nichel MD, Maruyama K, Uehara T, Miyagawa S, Kadoya M: Evaluation of hemodynamic imaging findings of hypervascular hepatocellular carcinoma: Comparison between dynamic contrast-enhanced magnetic resonance imaging using radial volumetric imaging breath-hold examination with k-space-weighted image contrast reconstruction and dynamic computed tomography during hepatic arteriography. Jan J Radiol 36(4): 295-302, 2018

13. Komatsu D, Yamada A, Suzuki T, Kurozumi M, Fujinaga Y, Ueda K, Kadoya M: Compartment model analysis of intravenous contrast-enhanced dynamic computed tomography in hepatic hemodynamics: a validation study using intra-arterial contrast-enhanced computed tomography. Hepatol Res 48(10): 829-838, 2018

14. Ohya A, Asaka S, Fujinaga Y, Kadoya M: Uterine cervical adenocarcinoma associated with lobular endocervical glandular hyperplasia: Radiologic- pathologic correlation. J Obstet Gynecol Res 44: 312-322, 2018

15. Yamada A, Fujinaga Y, Suzuki T, Komatsu D, Kitoh Y, Iwadate Y, Nozaki A, Ueda K, Kadoya M: Quantitative estimation of progression of chronic liver disease using gadoxetate disodium-enhanced magnetic resonance imaging. Hepatol Res 48: 735-745, 2018

16. Yamada A, Okajima Y, Yoshizawa E, Fukamatsu F, Mitsui T, Suzuki T, Ichinohe F, Oyama K, Todoroki K, Maehara M, Aonuma T, Nonaka T, Fujinaga Y, Kadoya M: Improvement in radiological reading efficiency and residents' education and clinical contribution using the modified reading system "Triage Reader". Jpn J Radiol 36(11): 649-660, 2018

17. Ozawa T, Koiwai K, Matsushita H, Kadoya M: Dosimetric comparisons of volumetric modulated arc therapy with three-dimensional conformal radiation therapy for locally advanced non-small cell lung cancer. The Shinshu Medical Journal 65(2):93-98. 2017

18. Yamada A, Komatsu D, Suzuki T, Kurozumi M, Fujinaga Y, Ueda K, Kadoya M: Evaluation of user input methods for manipulating a tablet personal computer in sterile techniques. Int J Comput Assist Radiol Surg 12(2): 339-349, 2017

19. Yoshizawa E, Koiwai K, Ina H, Fukazawa A, Sakai K, Ozawa T, Matsushita H, Kadoya M: Outcomes of uterine cervical cancer patients with pelvic lymph node metastases after radiotherapy without boost irradiation of metastases. J Obstet Gynaecol Res 43: 718-722, 2017

20. Yanagisawa S, Fujinaga Y, Watanabe T, Maruyama M, Muraki T, Takahashi M, Fujita A, Fujita S, Kurozumi M, Ueda K, Hamano H, Kawa S, Kadoya M: Usefulness of three-dimensional magnetic resonance cholangiopancreatography with partial maximum intensity projection for diagnosing autoimmune pancreatitis. Pancreatology 17(4): 567-571, 2017

21. Ohya A, Yamanoi K, Shimojo H, Fujii C, Nakayama J: Gastric gland mucin-specific O-glycan expression decreases with tumor progression from precursor lesions to pancreatic cancer. Cancer Sci 108(9): 1897-1902, 2017

22. Ohya A, Higuchi K, Shimojo H, Fujinaga Y, Kadoya M, Shiohara S: Epithelioid trophoblastic tumor of the uterus: A case report with radiologic-pathologic correlation. J Obstet Gynaecol Res 43(8): 1360-1365, 2017