Byincorporatinglivingorganismsintoman‐madesystemssuchasmachineparts,Iamworkingtodevelopnewtechnologiesthatdifferfromexistingmachinesystems.Forexample,Iamcurrentlyattemptingtocreatebio‐hybridrobotswithself‐assemblyandself‐repairfunctionsthatdonotrequireelectricityorfossilfuelsbyincorporatingmusclesintosystemsinsteadofmotors.Atthesametime,Iamalsodevelopingtechnologiesforoperatingcellsviamagneticfieldsandsystemsforfabricatingbiologicaltissuethatcanbetransplantedfromcells.Modernsocietyisdependentonfossilfuels,butexpertsonlyexpectthoseresourcestolastforabout150moreyears.Ifmusclescouldbeusedtopowerrobots,ourenergyproblemscouldberesolved.Additionally,theabilitytogrowthree‐dimensionaltissuethatcanbetransplantedfromiPScells,whichareabletodifferentiateintoallcelltypes,wouldcontributegreatlytothedevelopmentofregenerativemedicine.Ihavenotmentoredanygraduatesyetinmycurrentposition,butgraduateswhomImentoredinmypreviouspositionhavebeenemployedbymedicalequipmentandprecisionequipmentmanufacturers.AssociateProfessorYoshitakeAkiyamaAftercompletingagraduateprogramatTokyoUniversityofAgricultureandTechnology,AssociateProfessorAkiyamaworkedatJEOLLtd.,atTokyoUniversityofAgricultureandTechnologyasaspeciallyappointedassistantprofessor,andatOsakaUniversityasaseniorassistantprofessorbeforecomingtohiscurrentpositionin2014.Hisfieldsofspecializationincludebiotechnology,micromachining,regenerativemedicine,andtheintegrationofthesame.A?micro‐robot?walks?autonomously?(left)?while?a?micro?pinset?movesthrough?its?environment?(right),?both?using?muscle?tissue.An?illustration?(left)?and?overview?(right)?of?how?tissue?could?befabricated?from?cells?via?magnetic?fieldsCreating?new?bio‐hybrid?technologies?for?applications?ranging?from?micro‐robots?to?regenerative?medicineFrom?neurotrauma?to?neuroregenerationRepetitivebrainconcussioninplayingfootball,judo,andrugbyinducescognitivedysfunctionssuchasmemorydysfunction.Thebrainbecomesvulnerableandsensitivetostimulibyrepeatedheadcollisions,resultingindecreasingthethresholdofbraininjury.Therapiddeformationofbraintissueistypicallycausedbyheadimpactintrafficaccidentsbecausetheinertiaforceisappliedtothebraintissuebysuddenaccelerationanddecelerationofthehead.Therebyneuronsarestretched,andaxons,whichplayaroleinneurotransmission,areinjuredanddisrupted.Wehavedevelopedthecriteriaofaxonalinjurythroughtheimpactloadingexperimentofbrainneuronalcellstobetterunderstandthemechanismofaxonalinjuryinrepetitivebrainconcussion.Studentscanlearnthelogicalthinking,theproblemsolvingabilityandcommunicationskillsthroughstudyingautonomously.Theyalsocanenhanceaconnectionwithcollegersthroughthelifeoflaboratory.AssociateProfessorHiromichiNakadateAssociateProfessorNakadatetookhiscurrentpositionin2018afterworkingasanassistantprofessoratTokyoMetropolitanUniversity.Hisresearchfieldisbraininjurybiomechanics.Cell?stretching?device?for?reproducing?the?brain?deformation?in?head?impactThemeasuringaccuratelytheconditionandbehaviorofbraincellsexposedtomechanicalstressallowsustopredictbrainneurologicaldamagethatcannotbedetectedthediagnosticimagingsuchasCTandMRIbycomputationalsimulation,andthisstudyleadstoanoveldiagnosissystemandestablishingsafetycriteriaofautomobile.Axons?elongated?randomly?by?normal?culture?(left)?and?Axons?oriented?straight?by?controlling?adherence?property?of?culturing?surface?(right)26Department?of?Machinery?and?RoboticsBioengineeringDepartment?of?Machinery?and?RoboticsBioengineeringOutlook?for?researchOutlook?for?students?after?graduationOutlook?for?researchOutlook?for?students?after?graduation
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