応用生物科学科Researching?human?health?and?protection?of?the?freshwater?environment?and?analyzing?water?environment?changes?using?aquatic?insects?as?biological?indicatorsUsing?micromanipulation?to?study?the?mechanism?of?fertilization?and?preserve,?regenerate,?and?utilize?genetic?resources48OutlookforstudentsaftergraduationOutlookforstudentsaftergraduationWeareresearchingtherelationshipbetweenthebenthonicfaunaofthefreshwaterenvironment(i.e.,rivers,lakes,andmarshes)andwaterqualities(trophicstatus).Weusechangesinthecomposition,densitiesandbiomassofvariousspecies,andtheirroleintheaquaticecosystemtolearnandmonitorofthechangestothefreshwaterenvironment.Wecapturethesignalsgivenbyaquaticorganismstolearnaboutthecurrentwaterenvironmentandpredictfuturetrends.Coexistingwithnatureisagreatchallenge.Webelieveitisimportanttofindwaystodothisbybecominghighlyknowledgeableaboutnatureandlivingthings.Whynotbecomeanenvironmentalbiologist?Ourgraduatesareactiveasresearchersatresearchfacilitiesforpharmaceuticalcompanies,localpublicorganizations,pestcontrolcompanies,andwaterqualityinspectioncompanies,etc.ProfessorKimioHirabayashiProfessorHirabayashitookhiscurrentpositionin2007afterworkingasanassociateprofessorattheYamanashiWomen'sJuniorCollege,andasanassociateprofessorattheShinshuUniversity.HehasservedontheacademicstaffattheUniversityCollegeofLondonintheUKandontheassociateprofessorattheUniversityofMelbourneinAustralia.ResearchkeywordsincludeAppliedEcology,FreshwaterBiology,SanitaryZoology,andEnvironmentalHygiene.CarryingoutasurveyofaquaticinsectsintheAzusaRiver,theKamikochiSpecialProtectedArea,withpermissionfromtheMinistryoftheEnvironment.(Background:Mt.Yakedake)Chironomidlarvaeusedasanindicatorofaquaticenvironments.Carryingoutasurveyofbenthicfaunabydammingaportionofariver,aspartofajointprojectwiththePublicWorksResearchInstituteoftheMinistryofLand,Infrastructure,TransportandTourism.Outlook?for?research?Outlook?for?research?Inmylabwestudyphysiologicalaspectsofearlyeventsduringfertilizationinmammalsaswellastechnicalinnovationsinvolvingthepreservationandutilizationofgeneticresources.MystudentsandIhavepublishedmorethan100researchpaperssofardescribingourresearchintohaploidgametes(spermatozoaandoocytes)anddiploidembryosfromvariousmammalianspecies,includingmice,rats,rabbits,cats,horses,buffalo,cattle,whales,andhumans.Advancedreproductivetechnologiessuchasintracytoplasmicsperminjectionandsomaticcellnucleartransplantationmadeitpossibletobringthemammothbacktolife.Furthermore,wehaverecentlyestablishedpluripotentstemcelllinesinlaboratoryrats.IftheseESoriPScellscouldbedifferentiatedintofunctionalgametes,theprocesswouldbetheultimatetreatmentforinfertility.Graduatesareemployedbypharmaceuticalandfood‐relatedcompaniesaswellasnationalandlocalorganizations(aspublicofficials).Inwhathasbecomearecenttrend,someskilledgraduatesworkathumaninfertilityclinicsaspotentialembryologists.ProfessorShinichiHochiProfessorHochitookhiscurrentpositionin2008afterworkingasaresearcher(1986to1992)atSnowBrandMilkProductsCo.Ltd.,asavisitingassistantprofessor(1992to1995)andvisitingassociateprofessor(1995to1996)atObihiroUniversityofAgricultureandVeterinaryMedicine,andasanassistantprofessor(1996to1999)andassociateprofessor(1999to2008)intheFacultyofTextileScienceandTechnologyatShinshuUniversity.Heisengagedinresearchonreproductivephysiology,cryobiology,anddevelopmentalengineeringinsmallexperimentalrodents,largedomesticanimals,andhumans.Intracytoplasmicinjectionoffishhook‐shapedratspermheadswasdifficulttoachieve,butseveralclueshelpedusexpanditsapplicationtofreeze‐driedspermatozoa.Micromanipulationenablesustohandlenotonlyoocyteswithdiametersof100to120μm,butalsomuchsmallerspermcells.AmicrotubulenetworkcanbeassembledfromcentrosomeofspermatozoonimmediatelyafterfertilizationDepartment?of?Applied?BiologyDepartment?of?Applied?Biology
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