Outlook?for?research?Utilizing?Agrobacterium?tumefaciens,?which?carries?out?genetic?engineering?on?its?ownWild?type?VirE2Modified?VirE2NON‐transformantTransformant52応用生物科学科Department?of?Applied?Biology応用生物科学科OutlookforstudentsaftergraduationIamcarryingoutresearchonhowtouseA.tumefaciens,whichhastheabilitytoinsertitsownDNAintothechromosomesofplants,todevelopDNAinsertionmethodsfornumerouscrops;researchtoinfectplantswithA.tumefacienstocreateusefulsubstances;andresearchtoalterA.tumefaciensthroughgeneticengineeringtogivethebacteriumnewcapabilities.Inadditiontocreatingplantsthatdonotneedpesticides,wecancreaterawmaterialsforindustryandpharmaceuticals.Throughtheuseofgeneticallymodifiedplants,thesesubstanceswillbecreatedusingonlysolarenergyandCO2.Whilemanygraduatesareemployedbyfoodcompanies,othersworkatcomputerandchemicalcompaniesandaspublicofficials,forexampleasplantprotectionofficers.AssociateProfessorMasahiroNogawaAssociateProfessorNogawatookhiscurrentpositionafterworkingasanassistantprofessorattheNagaokaUniversityofTechnologyandasanassistantprofessorintheFacultyofTextileScienceandTechnologyatShinshuUniversity.Hisprincipalareasofresearcharegeneticengineeringandappliedmicrobiologyfocusingonplantsandmicroorganisms.VirE2proteintransfersforeignDNAintoplantnucleus.ModifiedVirE2proteinlocalizedinplastid(chloroplast).Blue:nucleus,Green:modifiedVirE2.Transformedmulberryproducedmorecytokininfromiptgenewhichintegratedintoplantgenomebyinplantamethod.Transformantdidnotshowapicaldominance.Outlook?for?research?Movingfromunderstandingoffunctionalbiomoleculestotheirapplication,utilizingunusedproteinresources,anddevelopingproductiontechnologiesTryingtocreatethefunctionallyimprovedproteins(e.g.higherenzymaticactivity),basedonthegeneticandproteinengineeringtechnologies.Weexploreandexaminetheusefulbiomoleculeswithvarioustechniques;astudentisisolatingthetargetproteinbyusingcolumnchromatography.応用生物科学科Department?of?Applied?BiologyOutlookforstudentsaftergraduationIamcarryingoutresearchonproteins,aprincipletypeoffunctionalbiomolecule.Mylabusesmolecularbiologyandgeneticengineeringtechnologytoidentifyandimproveusefulproteinssuchasenzymesandtodevelopprotein‐manufacturingtechnologies.Theidentificationofnewenzymesandtheirimprovementthroughgeneticengineeringareexpectedtocontributetomanydomains,includingfood,medicine,andchemicalsynthesis.Wearealsoattemptingtodeveloptechnologyformakingtheproductionofusefulproteinspossiblethroughalterationofribosomesandrelatedfactorsatthemolecularlevel.Manygraduatesareemployedasresearchersinavarietyoffields,includingbyfoodandpharmaceuticalcompaniesandchemicalmanufacturersthathandlevariousmaterials.AssociateProfessorTakaomiNomuraAssociateProfessorNomuratookhiscurrentpositionin2017afterworkingattheLionCorporationResearchCenterandasaresearchassociateandassistantprofessorintheFacultyofTextileScienceandTechnologyatShinshuUniversity.Hisprincipalareaofresearchistheanalysisoffunctionalbiomoleculesusingmolecularbiologyandgeneticengineeringtechnology.
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