?Engagement in clinical study and education as a radiologist Graduate students actively experiment. We can use experimental equipmentssuch as flow cytometry in our laboratory.Administration of a virus that multiplies only in cancer cellsEarly detection and early diagnosis by diagnostic imagingMinimum invasive therapy by IVR and irradiationAdvanced diagnostic imaging approaching function Curative radiation therapy preserving organ functionsNevus or Melanoma ? Can you diagnose ?17DermatologyProf.RyuheiOkuyamaRadiologyChallenging for next generation of melanoma treatmentDiagnosis & CureResearch subject?Assessment for melanoma patients using liquid biopsy?ICI effect predictors?Imaging diagnosis for melanoma using RGB values?Noninvasive diagnosis by measurement melanin in the nails.Outlook for researchSince malignant melanoma is one of the aggressive cancers, once it progress, complete remission is difficult. Even using immune checkpoint blockade, objective response rate is up to 30%. We hope that outcomes of our study contribute for improvement both of early diagnosis and treatment of advanced melanoma. Outlook for students after graduationYoucancontinuetheresearchinourlaboratoryorstudyabroad.Becausetheourresearchthemesarelinkedtomedicaltreatment,theknowledgeobtainedintheresearchisoftenusefulforclinicalpractice.TherearesomemembersinourlaboratorywhocontinueboththeresearchandclinicalpracticeafterthegraduationProf. YasunariFujinagaResearch subject?Early and differential diagnosis, pathophysiological analysis Outlook for researchOurmainprojectsarethediagnosticmethod,evaluationmethodofdiseasestatusandnewtreatmentmethodofmalignantmelanoma.Becauseprogressedmelanomaisdifficulttocure,earlydiagnosisandtreatmentareveryimportanttodistinguishtheearlymelanomafromthebenignpigmentednevus.Weaimtoestablishthenewdiagnosismethodsusingphotographsandanoninvasivemethodusingthenailpieces.Today,immunecheckpointinhibitors（ICI）andmoleculartargettherapyareoftenusedforthepatientssufferedfromprogressedmelanoma.WesearchforICIeffectpredictors.WealsodevelopvirotherapyagaintmelanomaincollaborationwiththeInstituteofMedicalScinence,TheUniversityofTokyo.Westudyfordevelopingnoveldiagnosticandtherapeuticmethodstosolveclinicalproblemsinourdepartment.Themainstudythemesareearlydiagnosis,differentialdiagnosis,andpathophysiologicalanalysisbydiagnosticimaging,developingnovelmethodsindiagnosticimaging,interventionalradiology(IVR),andradiationtherapy.Everyclinicalstudyisconductedincooperationwithotherclinicaldepartments.by diagnostic imaging?Development of novel methods in diagnostic imaging, IVR, ?Development of novel curative radiation therapy preserving and modalityorgan functionsEarlyrecognitionbyless-invasiveexamination;aclinical radiologist in a hospital.with a subspeciality in a university.forpatients.Sometimes,isdifficultitfunctionalthen,expectingcompletecurewithoutlossbyless-invasivetherapy.Ourstudiesinradiologydepartmentwillpromotebrightfutureinpatient-friendlymedicalcare.Outlook for students after graduation?Practicing diagnostic imaging, IVR, and radiation therapy as
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