Advanced 3D imaging for lung anatomyLung regeneration researchSurgical specimens of thyroid cancerExpression of EpCAM/CD44in thyroid cancer cell linesBreast & endocrine surgeryResearchin our laboratoryAlteration of protein expression in breast cancer cells発行：信州大学医学部信州大学医学部医学科Mammographic finding ofbreast cancer (arrow)発行年月：２０２４年７月21General Thoracic SurgeryChief: Prof. KimihiroShimizuBreast and endocrine surgerySurgerySurgeryAs a surgical oncologist, we aim to developetreatments for breast and thyroid cancer!Pursuing “Dual Missions” in Surgical MedicineOur department is committed to the “dual missions” of “healing patients” as physicians and “advancing research” as scientists. A surgeon must not favor one over the other. We strive to balance clinical excellence with scientific discovery despite the demanding nature of surgical work. We aim to be a leading center for thoracic surgery, fostering innovation and training the next generation of surgeons.Interaction between lung cancer and the microbiome;and breast cancer?Analysis of the mechanism by which cancer cells acquire resistance toantitumor drugs (drug resistance mechanism)Research subjectOur key areas of investigation include:?Advanced 3D imaging for lung anatomy (Figure);?CAR-T cell therapy for lunArialg cancer;??Lung regeneration using a rat sublobar resection model (Figure);?Spread through air spaces (STAS) of lung cancer.Outlook for researchLung cancer, being the leading cause of cancer-related deaths, is our primary research subject. Our goal is for all our research efforts to benefit each patient and to contribute to the future advancement of thoracic surgery.Outlook for students after graduationWe train "academic surgeons" who can conduct research on a wide range of questions and interests, from basic to clinical research, deepening their knowledge and understanding, and disseminating their findings to the world.Chief：prof.Ken-ichiItoResearch subject?Analysis of molecules involved in malignancy and progression ofthyroid Outlook for research?To be specialists of breast and endocrine surgery.?To be “academic surgeons” who have the creativity they need to thrive on the global stage. Outlook for students after graduationHavingcliniciansengageinresearchwhileyoungpreparesthemtofacethequestionsandproblemstheyexperienceintheclinic,letusshowtheworldtheclinicalandresearchsuccessesmadeatShinshu!treatmentforbreastandthyroidWemainlyprovidesurgicalcancers.Westrivetotrain“academicsurgeons”whocanprovidetreatmentbasedonascientificunderstandingoftumorsandcandevotethemselvestobasicmedicalresearchontumorsaswellasclinicalwork.
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