FromEMBOpressDevelopment specimen of the retina of a mouseThe retinal blood vessels are reflected in green. A fine blood vessel is very mysteriousA new blood vessel diluted with special liquid. The size changes depending on whether adrenomedullin works or does not work ...Members of the Department of Otolaryngology -Head and Neck SurgeryStudy on the protection and treatment of the cochlear nerve by DDS via cochlear implantAnalysis of the microenvironment of head and neck cancer by gene expression analysisElucidation of pathogenesis and development of novel gene therapy for human hereditary hearing loss modelsLaser device信州大学医学部医学科発行年月：２０２４年７月発行：信州大学医学部29OphthalmologyProf. Toshinori MurataOtorhinolaryngology –Head and Neck SurgeryTowards a new diagnosis and treatment of otological diseases and head and neck cancer!Future eye remedies? "Adrenomedullin"We are conducting both basic and clinical research. There is a substance in the body called adrenomedullin that dilates blood vessels, and recently it has been pointed out that adrenomedullin may improve retinal diseases. We are studying the effects of adrenomedullin on the eye. At the same time, we are analyzing data obtained in clinical settings to generate new findings.retinal diseases?Study of ophthalmic imaging and treatment outcomes in the clinical settingThe Department of Otolaryngology and Head and Neck Surgery deals with most of the sensory organs such as hearing, balance, smell, and taste. Of these, hearing is the most important communication tool for humans, and its impairment can greatly reduce Quality of Life (QOL) . In our department, we are conducting research on the mechanism of hearing loss and new treatment methods.The head and neck region, which includes the nasal cavity, oral cavity, tongue, pharynx, larynx, and cervical esophagus, controls important functions for human life such as olfaction, feeding, swallowing, and voice. Cancers that develop in each of these regions can greatly reduce QOL and even be fatal. We are conducting research to identify new therapeutic targets for head and neck cancers based on gene expression.Research subject?Study on the influence of adrenomedullin and its family peptides on the mouse Outlook for researchWiththeagingofsociety,eyediseasessuchasdiabeticretinopathyandage-relatedmaculardegenerationareexpectedtoincrease.Therearealreadyseveraltreatmentsforthesediseases,butinthefuture,adrenomedullinmaybecomeoneofthetreatments!Outlook for students after graduationAftergraduation,somecontinuetoworkasophthalmologistsinourhospital,whileothersconcentrateonclinicalpractice.Othersworkatothergeneralhospitalsoropentheirclinics.Prof. Yutaka TAKUMIResearch subject1. Study on the protection and treatment of the cochlear nerve by DDS via cochlear implant2. Development of database for diagnosis and treatment of otological diseases and development of novel AI diagnosis and analysis system3. Elucidation of pathogenesis and development of novel gene therapy for human hereditary hearing loss models4. Elucidation of factors and mechanisms of vestibular damage caused by progressive hearing loss5. Analysis of the microenvironment of head and neck cancer by gene expression analysis6. Study on the efficacy of cancer rehabilitation in patients with head and neck cancer7. A study on the diversity and regional characteristics of airborne pollen in Nagano PrefectureOutlook for researchNosinglefundamentaltreatmentforhearinglosshasyetbeenfound.However,researchinourdepartmenthasledtothediscoveryofnewtherapeuticmodelsforotologicaldiseases,whichmayhelpmanypatientswithhearinglossinthefuture.Inaddition,thediscoveryofnewtherapeutictargetsforheadandneckcancercouldgreatlyimprovecancertreatment.Wewanttodevelopfurtherapplicationsofourresultsandexplorenewtreatmentmethods.Outlook for students after graduationYouwillbeabletocontinueyourresearchwhilefurtheringyourclinicalstudiesattheuniversityhospital.Youcanalsostudyabroadordevelopyourresearchatdomesticresearchfacilities,andthedepartmentwillactivelysupportyou.
元のページ ../index.html#34