Optimization of individual pharmacotherapy based on the multiple evaluation of patient information（Naito T. Biol Pharm Bull 2019;42:149-57）TDM of cetuximab (anti-EGFR antibody) in head and neck cancer patients（Shibata K, et al. Cancer Chemother Pharmacol. 2021;87:555-65）The interprofessional education program by means of group work and roll play.Graduate students can conduct research at various professional development stages; early exposure, preclinical, clinical, postgraduate, and continuous development.信州大学医学部医学科発行年月：２０２４年７月発行：信州大学医学部35Clinical Pharmacology and TherapeuticsChief：Prof. Takafumi NaitoMedical EducationOurdepartmentcreatesthedruginformationforimplementingtherationalpharmacotherapyinclinicalsettings.Forthegoal,wedevelopthequantitativemethodsofdrugsinhumanbiologicalsamplesusingaliquidchromatographcoupledtomassspectrometer.Thepresentprojectsquantitativelyevaluatetheinter-individualvariationsinclinicalresponsestodrugsfromtheviewpointsofpharmacokineticsandpharmacodynamics.Wefinallyaimtoconstructtherationalpharmacotherapybasedonthefactorsrelatedtotheclinicalresponsestodrugsforeachdiseaseanditscondition.Medicaleducationinthe21stcenturyhasrapidlymodernized:fromexperience-basedtotheory-based,andfromspoon-feedinglecturestocollaborativetask-basedactivitiesinviewofsocialconstructivism.Withitseducationalactivitiesandrelevantresearch,CenterforMedicalEducationandClinicalTrainingcontributestofillingtheacademicandpracticalneedforclinicalprovidersandleadersinthehealthprofessions.curriculum.Itimprovedstudents’motivation.?Weclarifiedtutors’perceptionsinanoutreachactivityprogram.?Wedevelopedatestmanagementsystembycollaboratingwithacompany.Research subject?Development of quantitative methods of drugs in human biological samples?Evaluation of inter-individual variations in clinical responses to drugs?Construction of rational pharmacotherapy for the disease and its conditions?Detection of unknown adverse events and drug-drug interactions using non-experimental methodsOutlook for researchClarification of patient factors related to the pharmacokinetics, drug efficacy, and adverse reactions contributes to the individualization of pharmacotherapy. Our achievements lead to the construction of the rational pharmacotherapy for the disease and its conditions.Outlook for students after graduationAfterreceivinganacademicdegree,alotofourlaboratorygraduatesworkasaclinicalpharmacistorresearcher.Somegraduatescanbeengagedinthedrugdiscoveryresearchanddevelopmentatapharmaceuticalcompany.Research subjectPerceptions of health professions who are involved in outreach activitiesCurriculum reform and its influence on studentsInnovative collaborative/active learning approachesEducational assessment procedures for clinical clerkshipOutlook for research?WeinnovatedablendedgrouplearningandimplementeditintoapreclinicalOutlook for students after graduationBy achieving fundamental knowledge on medical education, you will be able to analyze your educational activities, and revise them.You will achieve quantitative and qualitative research methods.Creating the drug information for implementing the rational pharmacotherapy in clinical settingsHow to improve clinical practice?— The answer is: EDUCATION!
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