Operation subject?Optimization of animal experiments based on national regulations and rules World-class genetic testing system !!!Accuracy indicators !!!Tandemduplication30 kbTNXBTNXBnon-allelic homologous recombinationNew genetic testing technology for classical-like Ehlers-Danlos syndrome !!!Appearance of the institution of animal experiment. Laboratory animals are bred in the institution with appropriate breeding environment.Sleeping mice. Animal welfare is essential in scientific research.In vitro fertilization of mice. We can generate original gene-edited mice.REPORTATGCACCCAATCGCACTTTAT発行：信州大学医学部39Division of Clinical SequencingResearch Center for Advanced 基盤188bet体育_188bet备用网址支援センターDivision of Animal ResearchScience and Technology動物実験支援部門Divisional director: Prof. Yuji ShibaSpecially Appointed Prof. Osamu OharaResearch subject?ResearchonclinicalvalidityofgenetictestingatCenterforMedicalGenetics,Outlook for research?Development of a world-class genetic testing system all made in Japan?Contribution to sustain a community where people with hereditary or Research subject?Pathogenicitiesofinfectiousagentsinlaboratoryanimals(Dr.YamanakaH.)?PathologicalanalysisanddevelopmentoftreatmentmethodsforrarediseasesOutlook for researchFor many diseases there is still no cure. Appropriate animal experiments are essential for investigation of the diseases and will contribute to development of the therapeutic agent.Prof. Tomoki Kosho,Contribution to society with appropriate animal experimentsBest genetic testing for all Japanese patients!信州大学医学部医学科発行年月：２０２４年７月Genetictesting(clinicalsequencing)findssequencevariantsingenesthatmaycausehereditaryorcongenitaldisorders.“Divisionofclinicalsequencing”wasestablishedastheonlydivisioninJapanspecifiedforgenetictesting,supportedbyBMLInc.andLifetechnologiesJapanLtd.ofThermoFisherScientificInc.Themissionofthisdivisionistodevelopaworld-classandsustainablegenetictestingsystem,whichcanbetransferredtogenetictestingcompaniesandcontributetomedicalgeneticspractice.Forthemission,wetraingenetictestingspecialistsaswellasimprovegeneticanalysistechnologies.ShinshuUniversityHospital?Developmentofaccuracyindicatorsforgenetictestingusingnext-generationsequencing?Developmentofsimpleandhigh-resolutiongeneticanalysistechnologiesindifficult-to-sequenceregionscongenital disorders live happy livesOutlook for students after graduationThehighest-levelclinicalgeneticistinJapantoprovidecomprehensivesupportonpeoplewithhereditaryorcongenitaldisordersTheorgansandtissuesconsistofvarioustypesofcells.Andhomeostasisoflivebodyisregulatedwithcooperationofmultipleorgansandtissues.Then,animalexperiments,verificationwithlivebody,areessentialforunderstandingofpathophysiologicalmechanismsanddevelopmentofthetherapyofdiseases.Ontheotherhand,ethicalconsiderationandlegalcomplianceareimportanttheanimalexperiments.Ourmissioniscontributiontosocietywithappropriateanimalexperiments.in Shinshu University.?Support of animal experiments for researchers in Shinshu University.?Provision of information and special techniques for animal experiments.usingmodelanimals(Dr.YoshizawaT.)?Appropriatebreedingenvironmentforlaboratoryanimals(Mr.ShimadaS,Dr.YoshizawaT,andDr.YamanakaH.)forX30kbdeletion
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