（教授?菅野祐幸）【写真またはイラスト?サイズ：横幅3.3㎝程度?レイアウトは自由?上下2つエリアに分ける（図）】Deficiency of synaptogenicfactor Neurexins (TKO) in mouse cerebellum results in cerebellar hypotrophyTransfection of genes in neurons in mouse brain.A gene expressing a fluorescent protein is introduced in neurons in mouse cerebral cortexTraining in diagnostic pathology Man-to-man training with senior staffObservation of cultured cellsunder inverted microscopeBroad research approachnot restricted in morphology病理組織学4Cellular PhysiologyMolecular & 分子細胞生理学Exploring Synaptic Molecular Functions to Prof.Katsuhiko TabuchiPathologyUnravel the Etiology of Psychiatric DisordersResearch of EtiopathogenesisOurresearchiscenteredonthegenesthatgoverntheformationandfunctioningofsynapses,whicharetheconnectionsbetweenneuronsinthebrain.Inrecentyears,synapticdysfunctionhasbeenimplicatedintheonsetofneuropsychiatricdisorders.Weaimtoelucidatehowthesegenesoperatewithinsynapsesandhowtheirimpairmentsmayleadtoneuropsychiatricinvestigationsutilizegeneticallymodifiedmicetoexplorethesequestions.Theinsightsgainedfromourresearchwillcontributetotheadvancementofnoveltreatmentsforneuropsychiatricdisorders.Pathology,anunfamiliarresearchfield,clarifiesthediseaseprocesstodeath.Pathologistsobservethetissuespecimenssampledfromthelesionofpatients,givethediagnosisandfurthermakefinaldiagnosisafterautopsyexamination.Theycontributetotheadvancedmedicinethroughconferenceswithclinicians.Pathology,researchofetiopathogenesisofdiseases,makesthebasesofpathologicdiagnosis.Inourdepartment,wecandevoteinadvancedbiomedicalresearchwiththeprideofphysicianengagedinpatientcare.Contribution of innate immunity activated by various microorganisms?Epstein-Barr virus-related diseases: Diseases caused by ubiquitous virus in human beings in specific conditionsmechanisms?LowerfrequencyofcomplicationscausedwithimmunesuppressioninpatientsreceivingadvancedmedicalcareResearch subject-To investigate synaptic function in mouse models for mental disorders.-To elucidate the mechanisms through by synaptogenic molecules regulate synaptic function.-To advance genome editing techniques in neuronal cells.Outlook for research?Etiology of mental disorders will be elucidated.?Novel drugs targeting synapse will be developed.?Gene therapy for mental disorders will be developed.Outlook for students after graduation?Becomeamedicalresearcher.?Workinforeigncountrieswithforeignresearchers.?Becomeafacultyinuniversitiesoracademicinstitutes.Prof. Hiroyuki KannoResearch subject?Collagen disease, vasculitis, glomerulonephritis: Outlook for research?PreventionandtreatmentofintractablediseasescausedviaimmuneOutlook for students after graduation?Biomedicalresearchpositionsinpathologydepartmentinmedicalschool?Beneficialexperiencesintheresearchofhumandiseases?Diagnosticpathologistsinpathologydepartmentincenterhospitalsconditions.Our2024-2025医学科188bet体育_188bet备用网址紹介
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