Professor Takayuki Shindo of the Graduate School of Medicine Receives the 2014 Da Vinci Prize from the Healthcare Foundation Hakujikai
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Blood vessels are distributed throughout the whole body and play an essential role in maintaining vital functions. On the other hand, dysfunction of blood vessels is deeply involved in the 3 great lifestyle diseases of cancer, stroke, and heart disease. Furthermore, problems in the regulatory system that maintains the homeostasis of the blood vessels and failure of their repair processes could be the cause of various types of chronic organ diseases. The endothelial cells lining the blood vessels are central in maintaining homeostasis of the blood vessels. The endothelial cells lining the blood vessels produce various physiologically active molecules for maintaining the homeostasis within the body.
Professor Shindo has announced research results focusing on physiologically active factors secreted from the blood vessels and their receptor systems that are deeply involved in maintaining the homeostasis of each of the organs by using various genetically modified mice. The research results show the pathophysiological significance of bioactive peptides within the body that could lead to the therapeutic applications.
He has received the 2014 Da Vinci Prize from the Healthcare Foundation Hakujikai for research results on “Maintenance of Homeostasis of Blood Vessels and the Prevention and Treatment of Chronic Organ Diseases”.
